Breast Cancer Treatment

ANASTROZOLE (ARITOZ) 1MG Tablet

$70.00

This description provides a comprehensive overview of Anastrozole (Aritoz) 1 mg tablets, including indications, mechanism of action, administration, dosage, contraindications, warnings, precautions, adverse reactions, drug interactions, storage, and manufacturer information. Patients should consult their healthcare provider for personalized guidance on the use of Anastrozole.

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ANASTROZOLE ARITOZ

Description

Anastrozole is a medication categorized as a nonsteroidal aromatase inhibitor. It is formulated as tablets for oral administration.

Indications: Anastrozole is indicated for the treatment of hormone receptor-positive early breast cancer in postmenopausal women. It is also used for the adjuvant treatment of early breast cancer in postmenopausal women who have received two to three years of tamoxifen and are switched to Anastrozole for completion of a total of five consecutive years of adjuvant hormonal therapy. Additionally, Anastrozole is indicated for the first-line treatment of advanced breast cancer in postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer.

Mechanism of Action: Anastrozole inhibits the enzyme aromatase, which is involved in the biosynthesis of estrogen. By inhibiting aromatase, Anastrozole decreases the levels of estrogen in the body, thereby suppressing the growth of hormone receptor-positive breast cancer cells.

Administration: Anastrozole tablets are intended for oral administration. The recommended dose for adults is one 1 mg tablet taken once daily, with or without food.

Dosage and Administration:

• The recommended dose of Anastrozole for breast cancer treatment is 1 mg orally once a day.
• Treatment duration may vary depending on the specific condition being treated and the individual response to therapy.
• It’s crucial for patients to adhere to the prescribed dosage and regimen as directed by their healthcare provider.

Contraindications: Anastrozole is contraindicated in premenopausal women, pregnant women, women who may become pregnant, patients with a known hypersensitivity to Anastrozole, or any of its components.

Warnings and Precautions:

• Bone health: Anastrozole may cause a reduction in bone mineral density, leading to osteoporosis or fractures. Bone density should be assessed before initiating treatment and monitored regularly during therapy.
• Cardiovascular events: Anastrozole has been associated with an increased risk of cardiovascular events, including ischemic heart disease and stroke. Patients with preexisting cardiovascular disease should be closely monitored during treatment.
• Hepatic impairment: Anastrozole should be used with caution in patients with mild to moderate hepatic impairment. Close monitoring of liver function tests is recommended.
• Pregnancy and lactation: Anastrozole may cause fetal harm if used during pregnancy. It is not indicated for use in premenopausal women. Women should avoid becoming pregnant while taking Anastrozole and should use effective contraception during treatment.

Adverse Reactions: Common adverse reactions associated with Anastrozole treatment include hot flashes, asthenia, arthritis, pain, arthralgia, hypertension, depression, nausea, and vomiting.

Drug Interactions: Anastrozole may interact with medications that are metabolized by cytochrome P450 enzymes. It may also interact with estrogen-containing medications, such as hormone replacement therapy or oral contraceptives.

Storage: Anastrozole tablets should be stored at room temperature (25°C) in a dry place, away from direct heat and light. Keep out of reach of children.

Manufacturer: Aritoz tablets are manufactured by reputable pharmaceutical companies.

This description provides a comprehensive overview of Anastrozole (Aritoz) 1 mg tablets, including indications, mechanism of action, administration, dosage, contraindications, warnings, precautions, adverse reactions, drug interactions, storage, and manufacturer information. Patients should consult their healthcare provider for personalized guidance on the use of Anastrozole.